Outreach + Highlights

L’analyse de l’ADN ancien, permet de reconstituer des lignées généalogiques du passé afin d’étudier l’organisation familiale de nos ancêtres. Une étude récente avec l’analyse de 57 génomes datés de l’âge du fer a montré dans un village du sud de l’Angleterre que les couples vivaient près de la famille de la femme après le mariage.

African populations remain underrepresented in studies of human genetic diversity, despite a growing interest in understanding how they have adapted to the diverse environments they live in. In particular, understanding the genetic basis of immune adaptation to pathogens is of paramount importance in a continent such as Africa, where the burden of infectious diseases is a major public health challenge.

Since leaving Africa, human populations have gone through a series of range expansions. While the genomic signatures of these expansions are well detectable on a continental scale, the genomic consequences of small-scale expansions over shorter time spans are more challenging to disentangle.

Les élèves de la classe de Sébastien Vermot du collège des Rammes à Payerne ont entre 10 et 11 ans. Ils ont choisi de nous parler de la discrimination. Ninian Hubert Van Blyenburgh, anthropologue, répondra à leurs questions.

Liver cytochromes (CYPs) play an important role in drug metabolism but display a large interindividual variability resulting both from genetic and environmental factors. Most drug dose adjustment guidelines are based on genetics performed in healthy volunteers. However, hospitalized patients are not only more likely to be the target of new prescriptions and drug treatment modifications than healthy volunteers, but will also be more subject to polypharmacy, drug–drug interactions, or to suffer from disease or inflammation affecting CYP activities.

Chercheur à la Section de biologie (Faculté des sciences), Kostas Kampourakis est le lauréat du prix Friend of Darwin 2024, décerné par le National Center for Science Education (NCSE) basé aux États-Unis.

Whereas Mendelian genetics is an important research program in the life sciences, its school version is problematic.

Discussion sur la signification et l’interprétation des résultats communiqués par les compagnies qui réalisent ces tests ADN généalogiques, devenus très populaires.

A comprehensive knowledge of human leukocyte antigen (HLA) molecular variation worldwide is essential in human population genetics research and disease association studies and is also indispensable for clinical applications such as allogeneic hematopoietic cell transplantation, where ensuring HLA compatibility between donors and recipients is paramount.