Outreach + Highlights
The AGP laboratory conducts research on the diversity and biological evolution of human populations, with the main objective of reconstructing the history of world settlement since the origin of Homo sapiens.
Teaching School Genetics in the 2020s: Why "Naive" Mendelian Genetics Has to Go
Whereas Mendelian genetics is an important research program in the life sciences, its school version is problematic.
The most frequent HLA alleles around the world: A fundamental synopsis
A comprehensive knowledge of human leukocyte antigen (HLA) molecular variation worldwide is essential in human population genetics research and disease association studies and is also indispensable for clinical applications such as allogeneic hematopoietic cell transplantation, where ensuring HLA compatibility between donors and recipients is paramount.
Putting gene drives into context: Risks, depth of intervention, and regulatory challenges
Engineered gene drives are an emerging technology for the large-scale genetic modification of natural populations of species. They are controversial due to high levels of uncertainty about their risks and benefits.
Prevalence of yaws and syphilis in the Ashanti region of Ghana and occurrence of H. ducreyi, herpes simplex virus 1 and herpes simplex virus 2 in skin lesions associated with treponematoses
Yaws affects children in tropical regions, while syphilis primarily affects sexually active adults worldwide. Despite various campaigns towards the eradication of yaws and elimination of syphilis, these two diseases are still present in Ghana.
Modes d’analyse de la variabilité des fréquences des polymorphismes génétiques dans les populations humaines
Dans ce chapitre, nous introduirons quelques concepts de base en génétique des populations et présenterons certaines approches méthodologiques essentielles à l'analyse des données des polymorphismes sanguins étudiés dans les populations humaines.
Benefits do not balance costs of biological invasions
Biological invasions have profound impacts on biodiversity and ecosystem functioning and services, resulting in substantial economic and health costs estimated in the trillions of dollars. Preventing and managing biological invasions are vital for sustainable development, aligning with the goals of the United Nations Biodiversity Conference.
The effect of divergent and parallel selection on the genomic landscape of divergence
While the role of selection in divergence along the speciation continuum is theoretically well understood, defining specific signatures of selection in the genomic landscape of divergence is empirically challenging.
Benchmarking the Mantel test and derived methods for testing association between distance matrices
Testing the association between objects is central in ecology, evolution, and quantitative sciences in general.
Genetic surfing during the range expansion of an endangered large carnivore
In an effort to halt the global decline of large carnivores, reintroductions have become increasingly popular to establish satellite populations and reduce the risk of stochastic events.
Temporal variation in introgressed segments’ length statistics computed from a limited number of ancient genomes sheds light on past admixture pulses
Hybridization is recognized as an important evolutionary force, but identifying and timing admixture events between divergent lineages remains a major aim of evolutionary biology.